up against it   (TTS發音)

faced with a great difficulty or problem面臨極大的困難；經濟拮據

    He is very resourceful，but this time he was up against it. 他一向足智多謀，可這次還是遇到了極大的困難。

    My family is up against it because I can't find a job. 由于找不到工作，我家經濟拮據。